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Las nanopartículas magnéticas (mNPs por sus siglas, en inglés) han avanzado mucho en la última década hasta llegar a su desarrollo actual, ya se trate de dirigir un ejército de glóbulos blancos en su ataque a un tumor mortal o de influir en canales nerviosos específicos para inducir ciertos comportamientos como el latido del corazón.

Sin embargo, su futuro se presenta más brillante si cabe. Podrían jugar un papel fundamental en el desarrollo de herramientas que simultáneamente diagnostiquen, sigan y traten un amplio abanico de enfermedades y dolencias.

Las partículas multifuncionales, creadas siguiendo el modelo de partículas virales como la gripe y el VIH, están siendo investigadas para que puedan generar una señal que permita llegar a las áreas afectadas y poder tratarlas con mNPs.

Una selección de artículos publicados esta semana en Journal of Physics D: Applied Physics, muestran el alcance clínico de las mNPs en biomedicina y sus expectativas de futuro.

El componente magnético de estas nanopartículas está normalmente formado por un compuesto de hierro denominado óxido férrico, que en ocasiones utiliza, por ejemplo, ácidos grasos para mantener la estabilidad de las partículas. Las mNPs han despertado el interés de la comunidad científica después de asociarse a células madre y utilizarse como tratamiento de lesiones cardiacas en ratas.

La primera aplicación en seres humanos fue en 2007, en Alemania. Una técnica denominada hipertermia utilizaba mNPs para destruir un tipo especialmente agresivo de cáncer cerebral en 14 pacientes. La técnica consistía, básicamente, en calentar las células tumorales hasta matarlas.

Catherine Berry, una de los autores, afirma que “las nanopartículas magnéticas constituyen el principal campo de estudio para las futuras investigaciones de partículas multifuncionales”.

Fuente: www.diariomedico.com

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