Biochemical markers in Alzheimer’s disease clinical trials.

This article summarizes how biochemical markers may aid in the development of novel treatments that interfere with fundamental pathogenic processes in Alzheimer’s disease. Details are given on the potential use of biomarkers in Alzheimer’s disease clinical trials as additional inclusion criteria to enrich study populations with participants who really suffer from the disease, as a means to stratify study participants into meaningful subgroups that may benefit differently from the treatment, and as tools to detect desired biochemical effects and undesired side effects of the drug.

Fuente: Biomark Med. 2010 Feb;4(1):91-8.

This entry was posted on Saturday, July 3rd, 2010 at 11:19 and is filed under Alzheimer. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.

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