Una fosfatasa está ligada a la preservación de la integridad neuronal


Una enzima relacionada con la eliminación de fosfato se vincula directamente con la regulación de procesos neurodegenerativos, según publica hoy en Nature Neuroscience un equipo dirigido por Junko Sakaki, de la Universidad Akita, de Japón.

El inositol polifosfato fosfatasa 4a (INPP4A) protege a las neuronas de la muerte celular provocada por una excesiva activación del receptor del glutamato. Los ratones que carecen de esta enzima sufren apoptosis neuronal en el estriado y experimentan movimientos involuntarios.

La muerte celular excitotóxica ya se había vinculado con el Parkinson y la corea de Huntington. Sakaki cree que esta proteína preserva la vida celular desregulando receptores del glutamato.


36 Responses to “Una fosfatasa está ligada a la preservación de la integridad neuronal”

  1. name with the blogger blog, but the

    website name will be yourblogname.blogspot.com rather than yourblogname.com.ownership: you will never really own your blogger blog as the data files and content are hosted on blogger’s server.wordpress stands out as the other well-liked platform for b…

  2. only advice would be, to choose a

    writer who’s first language is english. with in a few days of posting the job you will receive many bids, some will offer to complete the project for $50, other freelance writers will offers bids which are less than the $50.

  3. profit. these days, we come across a

    lot of content in the newspapers, in magazines, in journals and in websites. when we read these articles, we gain new insights or form opinions and also get encouraged to take decisions.many articles even encourage us to try out various products

  4. makeup says:

    service has what is called a cpanel

    and within this cpanel you can find a “one click” method by which you can quickly install your own wordpress blog.this has proven to be very revolutionary. it has become a road by which anyone can have their own blog and

  5. buy tag away says:

    and sources to get people to your

    site and we’ll show you exactly how to do it.#1) improve your seo – let the search engines send you trafficif you optimize your website for the search engines you are a lot more likely to get “organic” traffic from google

  6. Mel says:

    ways to earn money online. make use

    of this opportunity to attract visitors to your blogs. if the content is worth it, they may even subscribe to your feeds or recommends the page to a friend.’how to’ content – a lot of new members are also searching on

  7. to read. you wouldn’t write a book

    without a structure so why a blog, plan what you will write and how you can make it better. edit where the widgets will be on your site and make sure the writing (the main content) is where the reader can

  8. Look At This says:

    just write something real quick to let

    them know what is going on. be unique, don’t copy others content unless you ask to use something, i have seen this often. some blogs will have your exact content repeated, i have had this happen to me. it’s fine to

  9. think these 8 tips will help you

    to change your blog completely, and boost its performance. i see the future of america as a society that is knowledge-based competing and succeeding in the changing dynamics of the modern world. creating a knowledge-based society involves getting all p…

  10. best hgh says:

    the customer. this letter is friendly, personal

    and sales structured. however, what if you are a credit manager and you have to write a fourth letter to a dealer who appears to have no intentions of paying an account that is months past due. in this situation business,

  11. Source says:

    you good search engine traffic, so you

    can’t go wrong with the seo aspect of things. but try it out for yourself and see which one you like best. do it now.good luck with using blogging in your business today. do you like blogging? i do. blogging is

  12. do some research. read forums or do

    keyword research.3. simple words, simple phrases, short sentences – writing for internet means that you are writing for the whole world. your readers come from different countries and therefore they all have different reading capabilities. the more sim…

  13. choice for english majors and other students

    whose future employers may value creativity. creative writing may even help students to do better in their more academically rigorous coursework.most colleges and universities with a comprehensive english department are able to offer some kind of creat…

  14. doing.5. always be willing to change. some

    people get stuck writing a certain way. they use the same language in every one of their articles. do not do this. in fact, the search engines will look down upon this type of writing. instead, make sure that you are

  15. of any unseen problem. at the top

    of your home page, twitter asks “what are you doing?” what it’s really asking, though, is what are you doing that has any value to anyone else. if you’ve used the micro-blogging service to any extent, you know far too many

  16. platforms that concentrate of defined subject matter

    and if it is of interest to them they’ll return. the focus needs to be there to build traffic which you can then develop into loyal subscribers!manage your timeblogging is a long term process therefore you must learn to manage your

  17. authors both past and present. students may

    also explore what it means to be a contemporary writer or artist, bringing elements of philosophy to the creative writing curriculum.of course, not every english major is a good creative writer. even those who find that their best writing occurs in

  18. have you ever heard of the program

    “google adsense”? if not, then let me tell you about it real quick. it’s a program where you host ads on your website or blog, and whenever someone clicks on your ads, you earn a small commission for it. now this

  19. posts. doing so will dramatically decrease your

    readership, and cause people to think you don’t know what you are talking about. instead, write blog posts that are full of paragraph breaks and extra spaces. this will make it easy on your readers eyes, causing your traffic to increase.getting

  20. make, taste great and will give your

    body all the nutrition it needs. baked chicken breast with rice or pasta a bagel with peanut butter potato steamed or baked with a topping of low fat cheese and some fruit.5. what should you drink post-workout?a lot of people have

  21. the writing (the main content) is where

    the reader can see it. look at other blogs to see what structure they use and see how you can use this with your site. remember you can always edit your blog, and change things around, nothing is set in stone.

  22. word out about your site outside just

    the internet.you could consider offering some kind of prize draw as an incentive for people to visit your site and let you have their name and email address – the prize could be a simple money off coupon or something more

  23. the basis of your success.without this foundation

    in place, you’re building in a swamp.take time to consider these questions deeply, and boil your answers down further and further to reach the highest level of clarity understanding possible.#4 – dedicationsuccessful bloggers and entrepreneurs are not…

  24. of the person, even if you really

    liked that person? i bet the answer is yes. and the writing that left such a poor impression on you probably was that way because the author either did not take the time to edit his writing, or tried but didn’t

  25. batch of content.a blog is nothing without

    worthwhile content. if you can’t somehow move the story forward in some way, then you are missing out on a great opportunity. consider what others are doing, but don’t dwell on it. your site is your site, and it should be

  26. link removed ]i could keep going. the

    list is endless. however, as you can see, the number one way to not get you comment approved is to not add value to the page. what exactly does this mean. well, commenting on blogs is a way to promote dialogue

  27. Comtrol says:

    you can go about getting lots of

    ideas for free. i might also talk a little about outsourcing content creation! comments and replies to blog posts and articles are welcome when done correctly.most of us that blog and write articles are happy to receive comments about our work

  28. occupation is, their hobbies, interests, languages, etc.

    that will help you much if you want to add humor to your blog article. yes, sense of humor is very much appreciated not only in circus and soap operas. even dr. house cracks off jokes all the time – this

  29. online, i would answer your question and

    then go back to my blog and type something like…”a good friend asked me a good question the other day and i thought it was important enough to share with you. they were wondering the first thing they need to do

  30. dana pensiun says:

    kind of content for your website.the writer

    you plan on hiring must have a proper knowledge of seo so that the content is keyword based. he should have a huge database of online marketing. the writer must be conversant with the style of writing in internet marketing. hire

  31. simple truth has gotten buried… writing a

    good article is still the best way to build traffic, gain a solid reputation, and take your online success to new heights.having been an article writer and marketer for over a decade, i can tell you with certainty that the best

  32. aktualne.me says:

    number of character for description and the

    display order (random, new, and old). using this tool, you can have a powerful admin back-end where you can control the order in which the articles will appear and the plug-in will always call the first image from the featured post

  33. start by identifying a keyword that is

    high demand but low competition.the importance of finding the right keyword is to accurately identify the target group you are trying to reach. this is the first step because if you misidentify your keyword your content won’t get seen by the

  34. noticias says:

    who doesn’t like to find out if

    a product is worth the money or not? let your audience have a sneak peek. expand on a comment left on your blog. comments can spark great discussion and even better blog posts! give a tip list. just like this one.

  35. i have a feed based on ‘blogging

    tips’, any new articles or posts that are written about blogging tips, i get them.i open up the links and read through the articles to see if they are worth sharing. i also get great ideas for articles and posts if

  36. from a friend who loved it so

    much that i was intrigued enough to buy a copy. this friend had been told about it by a friend who had been told about it by a cousin who had been told about it by a sister. soon the friend

Leave a Reply

You must be logged in to post a comment.