“We have developed a low-cost behavioral assessment that can clue someone in to Alzheimer’s disease at its earliest stage,” said Michael Wenger, associate professor of psychology at Penn State. “By examining (information) processing capacity, we can detect changes in the progression of mild cognitive impairment (MCI).”MCI is a condition that affects language, memory and related mental functions. It is distinct from the ordinary mental degradation associated with aging and is a likely precursor to the more serious Alzheimer’s disease. Both MCI and Alzheimer’s are linked to a steady decline in the volume of the hippocampus, the area of the brain responsible for long term memory and spatial reasoning.MRIs — magnetic resonance imaging — are the most reliable and direct way to detect hippocampal atrophy and diagnose MCI. But for many, the procedure is unavailable or too expensive.
“MRIs can cost hundreds of dollars an hour,” Wenger said. “We created a much cheaper alternative, based on a memory test, that correlates with hippocampal degradation.” Wenger and his collaborators at the Mayo Clinic College of Medicine, Rochester, Minn., detail their findings in the current issue of the Journal of Mathematical Psychology.
From a computer model of an atrophying hippocampus, the researchers determined how to estimate capacity with a statistical measure of how quickly tasks are completed. Applying this analysis to a memory test for people with MCI, the researchers were able to gauge their hippocampal capacity and compare it to the progression of their ailment.
“My collaborators at the Mayo Clinic backed up this study with MRIs for the MCI group,” Wenger said. “These capacity measures we developed showed a reliable relationship to the hippocampal volume measurements, so we know we are on the right track.”
The scientists began by modeling the hippocampus as a complex electrical circuit. Equations governing electric current and voltage mimicked the electrical firing of neurons within the circuit. The researchers switched off neurons in the simulation to model atrophy of the hippocampus.
With fewer cells available to process electrical signals, the model hippocampus slowed down, but its capacity for processing information decreased at an even faster rate. Capacity was the most sensitive measure of how the hippocampus was deteriorating, more than the average processing speed.
“We then applied this to the gold standard of the field — the Free and Cued Selective Reminding Test (FCSRT),” Wenger said. “This is a test that can discriminate between normal age-related memory changes and changes caused by impairment.”
The researchers gave this test to five groups of participants: college students, healthy middle-aged adults, healthy elderly individuals, people with diagnosed cases of MCI and a control group of age-matched individuals without MCI. The first three groups each had 100 members and the last two each had 50.
During the FCSRT, the researchers showed the participants descriptive words, such as “part of the body” and “artery,” and asked the participants to choose the picture that fit these cues from a set of 24 images, in this case, a picture of a heart. The psychologists then asked the subjects to recall as many items as they could. For objects they failed to remember, the psychologists provided the category cues, providing more information and testing the limits of the subjects’ capacity.
The researchers analyzed the response times for the tasks and the number of items that were recalled, with and without additional cues. The MCI group showed the greatest sensitivity to added cues — the additional input either substantially helped or inhibited their performance. But like the computer model, estimates of capacity highlighted the greatest cognitive difference between the MCI group and the others.
This study’s approach to defining processing capacity is unusual. The scientists combined disparate principles of engineering and statistics, mathematically translating processing capacity into what is called the “hazard function.”
The hazard function is well known in engineering, but relatively new for fields like psychology. It gives the probability that a task that is not yet completed will be completed in the next interval of time.
By measuring how long it takes a participant to recall the objects during the FCSRT, the psychologists fit a model based on the hazard function to each participant and obtain a measure of his or her capacity for the memorization task.
The difference in hazard function measures between the MCI group and all other groups was statistically much more pronounced than the differences between all groups in the number of items they recalled. These hazard function differences also outweighed the contrasts between all groups in their response times. The hazard function model proved to be the most sensitive diagnostic for cognitive distinctions in the groups, making it a reliable indicator of capacity and a better signal of the underlying hippocampal atrophy than processing speed alone.
The researchers’ results are valid for every person, not just for the whole group. Since the modified FCSRT relies on personal reaction times, hazard analysis and performance, it can track the progression of MCI for anyone, anywhere there is access to a computer.
FUENTE: www.familyhealthguide.co.uk
Not fake…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
http://publishbookmark.com/story.php?title=californiapsychics-com-complaints…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
online psychics…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
http://www.kcbmc.biz/xe/?document_srl=255852…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
voyant gratuit…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
voyance par telephone…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
simply click the up coming document…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
voyance discount…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
rebelmouse.com…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
medium…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
Will Pc Computer Game Controller Wireless Work For Mac…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
Louis Vuitton Bags…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
Louis Vuitton Artsy Hobo…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
Sac Louis Vuitton Lausanne…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
voyant…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
films x…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
Lance Moore Jerseys Youth Reebok…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
click here to investigate…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
voyance en ligne gratuite…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
redirected here…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
click to read…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
Wii U Vs Ps4 Vs Xbox One Yahoo…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
voyance gratuite en ligne amour…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
Voyance Gratuite…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
tirage tarot gratuit…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
voyance gratuite en ligne…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
tirage de tarot gratuit…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
cheats for saints row iv…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
satellite tv dish…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
el pene mas grande…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
aumento peniano…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
gopro hd…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
penisstorre.se…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
Plants vs Zombies 2 cheats…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
xtrasize…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
Garcinia Cambogia…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
car insurance scams…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
casino…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
Our Home Page…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
candy crush cheats…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
azilo…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
kredittkort…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
duży członek…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
powiększenie penisa…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
http://www.fatlosscare.org/how-to-lose-10-pounds-in-a-week-lose-ten-pounds-in-a-week/…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
Dental Equipment…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
gta iv cheat…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
ultrasound Guide…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
fresh healthy vending complaints…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
tens unit…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
Watch Free movies online…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
film porno gratuit…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
voyance en direct gratuit…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
subway surfers cheat…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
xnxxcom…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
dragon city hack…
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS…
Hill Climb Racing
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
click through the up coming document
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
best psychic reader
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
candy crush triche
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
just click the up coming article
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
nashville painting company
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
http://www.sssmep.cz/new/wiki/index.php/Psychic_Readings:_The_Path_To_Clarity
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
underwater camera
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
sneak a peek here
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
1
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
gotowkowy.eu
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
Free Sex
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
twenty times day
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
what to get mom for christmas
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
beats cyber monday
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
domain
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
porno hub
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
voyance immediate
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
applanet apk
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
vitiligo treatment
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
moncler jackets
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
Ipad Mini
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
http://dimitriavenir.com/
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
voyance gratuite immediate par tchat
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
uggs Cyber Monday Deals
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
kitchen design
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
voyance gratuite
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
voyance gratuite amour boule de cristal
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
Bel Air 5s
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
ralph lauren uk
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
website
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
browse around these guys
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
canada goose nettbutikk
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
you can find out more
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
jeux de guerre
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
canada goose italia
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
canada goose jakke
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
dirt devil ud790095
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
voyance gratuite immediate
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
canada goose online
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
relevant internet page
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
http://www.youtube.com/watch?v=Um3oDeVSVfk
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
canada goose outlet
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
jeux de filles
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
relevant web page
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
pop over to this website
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
canada goose outlet toronto
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
home improvment
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
voyance gratuite par chat
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
je recommande votrevoyancegratuiteendirect.info
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
tarot de marseille gratuit
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
voyance gratuite tarot
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
tirage de tarot
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
simply click the up coming web site
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
voyance gratuite en ligne
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
cheapest canada goose jacket
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
canada goose jacket
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
click through the up coming webpage
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
ugg soldes
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
doudoune canada goose
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
ugg boots sale france
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
http://www.iamsport.org
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
bottes ugg femme
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
studio reklamy lubin
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
canada goose jackets outlet
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
horoscope de demain
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
goose jackets
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
radiology technician schools
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
http://nael-voyance.com
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
ugg boots france
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
kjøp canada goose
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
voyance gratuite amour
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
davidvoyance.fr voyance par email
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
voyance gratuite immediate par telephone
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
voyance gratuite flash
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
visitez roccovoyance.fr
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
wijsbegeerte.org
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
audreypoitiers.com voyance immediate
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
ultrasound technicians
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
bottes ugg pas cher france
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
http://1url.com/
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
pregnancy miracle success
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
canada goose femme ebay
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
http://www.pinterest.com/pin/312226186637961996/
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
stivali ugg outlet online
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
stivali ugg outlet donna
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
North Face Black Friday
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
stivali ugg online
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
bottes ugg pas cher solde
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
voyance gratuite tchat
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
distance education
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
http://www.patriciawestergard.com
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
moncler jas outlet
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
ugg uitverkoop
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
moncler jacken
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
ugg netistä
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
moncler jassen amsterdam
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
web site
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
ugg outlet italia
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
doudoune canada goose chilliwack homme
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
moncler jacken outlet
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
click for more info
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
cheap dr dre beats
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
beats by dre uk
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
cheap beats uk
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
beats uk
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
dr dre beats
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
Vemma Scam
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
Beats by Dre Outlet
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
ugg boots cheap
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
uggs cheap
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
divorce
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
Stivali Ugg
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
Moncler Online
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
Read the Full Article
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
Moncler Outlet
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
doudoune moncler pas cher
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
http://www.natureisletube.com/read_blog/115377/ideas-and-tricks-for-enhancing-your-after-that-travel-practical-experience
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
check out the post right here
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
Click At this website
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
moncler pas cher
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
zzzz
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
best elo boosting service
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
http://wiki.nacta.edu.cn/
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
serrurier paris
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
tinnitus cure in rats
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
amanet electronice
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS
tinyurl.com
A New, Inexpensive Way to Predict Alzheimers Disease « GECOTEND NEWS