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El talento, en buena medida, es una cuestión de insistencia

       Francisco Umbral 

  Un equipo con participación de científicos del Consejo Superior de Investigaciones Científicas (CSIC) ha hallado un nuevo proceso molecular según el cual los glóbulos blancos amplifican la respuesta inmunitaria.

Los investigadores han observado que los linfocitos T, encargados de reconocer moléculas que forman parte de un patógeno (antígenos) y activar el sistema inmune, son capaces de devorar estas moléculas y de exponerlas a otros linfocitos T. El estudio, publicado en la revista Immunity, podría servir para una futura utilización de los linfocitos T como una vacuna viva.

Hasta ahora se conocía la capacidad de los linfocitos T para reconocer moléculas expresadas por células infectadas con virus o células que han atrapado otro tipo de microbios. “Los linfocitos T también tienen capacidad fagocítica, es decir, que son capaces de devorar un antígeno. Además, lo exponen en su propia membrana para que otros linfocitos T lo reconozcan. Son, por tanto, ejecutores y, al mismo tiempo, desencadenadores de la respuesta inmunitaria”, explica Balbino Alarcón, investigador del CSIC en el Centro de Biología Molecular Severo Ochoa.

Los científicos hallaron este proceso al estudiar la función de la proteína TC21, la cual ha resultado ser “fundamental” en la fagocitosis que llevan a cabo los linfocitos T. Además, es necesaria otra herramienta molecular, la proteína RhoG.

Fuente:http://wwww.diariomedico.com

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